Atlantic Endocrinology New York City

Can a Mammogram Detect Paget’s Disease

Mammograms are a crucial tool in the early detection of breast cancer, but can they also detect Paget’s disease of the breast? Paget’s disease is a rare type of breast cancer that often presents with symptoms like itching, burning, or changes in the nipple and areola. In this article, we will explore what Paget’s disease is, its symptoms, how it differs from other breast conditions, and whether a mammogram can detect it.

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Can a Mammogram Detect Paget's Disease

Can a Mammogram Detect Paget’s Disease?

Mammograms are highly effective in detecting breast cancer, particularly when it comes to identifying abnormalities within the breast tissue, such as masses or microcalcifications. However, Paget’s disease of the breast primarily affects the skin and nipple, and mammograms may not always capture these changes effectively.

In some cases, Paget’s disease may be associated with underlying breast tumors or ductal carcinoma in situ (DCIS), which can be detected on a mammogram as suspicious calcifications or masses. Still, the skin and nipple changes characteristic of Paget’s disease are often missed by mammography.

The Role of Imaging in Paget’s Disease Diagnosis

While mammograms may not be the primary tool for diagnosing Paget’s disease, other imaging modalities can be used in conjunction with clinical examination to aid in diagnosis. These may include:

  • Ultrasound: Ultrasound can provide a detailed view of the nipple and areolar region, which may help detect abnormalities associated with Paget’s disease.
  • Magnetic Resonance Imaging (MRI): MRI can offer enhanced imaging of the breast tissue and may help identify underlying tumors or areas of concern.
  • Biopsy: The definitive diagnosis of Paget’s disease is made through a skin biopsy, where a sample of the affected skin and underlying tissue is examined under a microscope.

How Is Paget’s Disease Different from Other Breast Conditions?

Paget’s disease of the breast can mimic other benign skin conditions or even eczema. However, it is fundamentally different because it is associated with an underlying breast cancer, often ductal carcinoma in situ (DCIS) or invasive breast cancer.

Other benign skin conditions that may mimic Paget’s disease include dermatitis, psoriasis, or fungal infections. These conditions usually respond to topical treatments and do not involve cancer.


In summary, while mammograms are excellent tools for detecting breast cancer, they may not be the primary method for identifying Paget’s disease of the breast. This rare form of breast cancer primarily affects the skin and nipple, and its symptoms are often missed by mammography.

If you experience persistent symptoms such as redness, itching, burning, or changes in your nipple and areola, it is essential to consult a healthcare provider promptly. They can perform a clinical examination, and if necessary, order additional imaging tests like ultrasound or MRI. A skin biopsy may ultimately be required to confirm the diagnosis.

Early detection and timely intervention are crucial for effectively managing Paget’s disease of the breast and improving outcomes. If you have concerns about breast health or notice any unusual changes, do not hesitate to seek medical attention and discuss your symptoms with a healthcare professional.

FAQs (Frequently Asked Questions)

Is Paget’s disease of the breast common?

No, Paget’s disease of the breast is considered rare, accounting for a small percentage of all breast cancer cases.

What is the prognosis for Paget’s disease of the breast?

The prognosis for Paget’s disease depends on various factors, including the extent of underlying breast cancer. Early detection and appropriate treatment are essential for a better prognosis.

Can Paget’s disease affect both breasts?

Yes, it is possible for Paget’s disease to affect both breasts, although it is relatively rare.